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KMID : 0357919760100020255
Korean Journal of Pathology
1976 Volume.10 No. 2 p.255 ~ p.260
A Case of Sacrococcygeal Endodermal Sinus Tumor
ÀÌ¿Á¼±/Ok Sun Rhee
ÀÌÀ¯º¹/À̺À¿µ/ȲÀÇÈ£/Ȳ±Ôö/Yoo Bock Lee/Bong Yong Lee/Eui Ho Whang/Kyu Chul Whang
Abstract
Endodermal sinus tumor is a rare neoplasm and microscopically characterized by a
glomerulus-like structures. It was first described by Schiller in 1939 under the
designation of mesonephroma because of microscopic structures resembling mesonephric
glomeruli. Kazancigil et al.(1940), however, considered the glomerulus-like structures to
be papillary and endothelial in nature and do not represent attempted formations of true
glomeruli. Teilum(1952, 1965) observed similarity between papillary formations in the rat
placenta and this tumor of human ovary. These papillary structures in the rat had been
called endodermal sinuses by Duval (1891) because he considered them to represent
diverticula of the yolk sac growing into extraembrynoic mesenchyme.
Endodermal sinus tumor hag generally been reported to be in the ovary and testis and
often in association with teratomatous areas. Very few cases of endodermal sinus tumor
originating from extragonadal sites such as anterior mediastinum, pelvis, pineal gland
have been described. In 1964, Rao et al. first reported the endodermal sinus tumor of
sacrococcygeal area from a 3 years old girl under the title of sacrococcygeal
mesonephroma. Our case is a 4 year old girl and complained pain and slow glowing
mass of sacrococcygeal area for 2 months. Except for a palpable mass at sacrococcyx,
all other physical examinations were negative including pelvic organs. Barium enema
showed soft increased mass shadow in the buttock and somewhat increased presacral or
retrorectal space. No evidence of bone destruction in the sacrum is noted. Excision of
the mass was performed. Histologic examination revealed the typical picture of sinus
tumor without the evidence of teratomatous component. Since there was no evidence of
ovarian involvement, the lesion was regarded as a primary sacrococcygeal endodermal
sinus tumor.
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